C1orf86 (FAAP20) (NM_182533) Human Mass Spec Standard

SKU PH315561

C1orf86 MS Standard C13 and N15-labeled recombinant protein (NP_872339)

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: [RC215561]
• Predicted MW: 19.6 kDa
• Protein Sequence:
  Protein Sequence

  >RC215561 representing NM_182533; Red=Cloning site Green=Tags(s); ; MEAARRPRLGLSRRRPPPAGGPSGGRPWFLLGGDERERLWAELLRTVSPELILDHEVPSLPAFPGQEPRC; GPEPTEVFTVGPKTFSWTPFPPDLWGPGRSYRLLHGAGGHLESPARSLPQRPAPDPCRAPRVEQQPSVEG; AAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_872339
• RefSeq Size: 745
• RefSeq ORF: 540
• Synonyms: C1orf86; FP7162
• Locus ID: 199990
• UniProt ID: Q6NZ36
• Cytogenetics: 1p36.33
• Summary: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.[UniProtKB/Swiss-Prot Function]