Dystrophin (DMD) (NM_004018) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC215529 |
| Predicted MW | 70.6 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004009 |
| RefSeq Size | 4552 |
| RefSeq ORF | 1866 |
| Synonyms | BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85 |
| Locus ID | 1756 |
| UniProt ID | P11532 |
| Cytogenetics | Xp21.2-p21.1 |
| Summary | This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. provided by RefSeq, Dec 2016 |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Dystrophin" proteins (16)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH313926 | DMD MS Standard C13 and N15-labeled recombinant protein (NP_004012) | 10 ug |
$3,360.00
|
|
| LC418275 | Lyophilized DMD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418276 | Lyophilized DMD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418277 | Lyophilized DMD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418278 | Lyophilized DMD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418279 | Lyophilized DMD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418281 | Lyophilized DMD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418275 | Transient overexpression lysate of dystrophin (DMD), transcript variant Dp71 (as WB positive control) | 100 ug |
$665.00
|
|
| LY418276 | Transient overexpression lysate of dystrophin (DMD), transcript variant Dp71b (as WB positive control) | 100 ug |
$665.00
|
|
| LY418277 | Transient overexpression lysate of dystrophin (DMD), transcript variant Dp71a (as WB positive control) | 100 ug |
$665.00
|
|
| LY418278 | Transient overexpression lysate of dystrophin (DMD), transcript variant Dp71ab (as WB positive control) | 100 ug |
$665.00
|
|
| LY418279 | Transient overexpression lysate of dystrophin (DMD), transcript variant Dp40 (as WB positive control) | 100 ug |
$436.00
|
|
| LY418281 | Transient overexpression lysate of dystrophin (DMD), transcript variant Dp140b (as WB positive control) | 100 ug |
$665.00
|
|
| TP313926 | Recombinant protein of human dystrophin (DMD), transcript variant Dp140b, 20 µg | 20 ug |
$867.00
|
|
| TP315529 | Recombinant protein of human dystrophin (DMD), transcript variant Dp71ab, 20 µg | 20 ug |
$867.00
|
|
| TP762385 | Purified recombinant protein of Human dystrophin (DMD), transcript variant Dp427m, Lys3200-Thr3684, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
Citations
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