NFH (NEFH) (NM_021076) Human Mass Spec Standard

CAT#: PH313487

NEFH MS Standard C13 and N15-labeled recombinant protein (NP_066554)


  View other "NFH" proteins (4)

USD 3,255.00

In Stock*

Size
    • 10 ug

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Frequently bought together (2)
Transient overexpression lysate of neurofilament, heavy polypeptide (NEFH)
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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213487
Predicted MW 111.7 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_066554
RefSeq Size 3695
RefSeq ORF 3060
Synonyms CMT2CC; NFH
Locus ID 4744
UniProt ID P12036
Cytogenetics 22q12.2
Summary Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Protein Families Druggable Genome
Protein Pathways Amyotrophic lateral sclerosis (ALS)

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