TRIB2 (NM_021643) Human Mass Spec Standard

SKU
PH301210
TRIB2 MS Standard C13 and N15-labeled recombinant protein (NP_067675)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201210
Predicted MW 38.8 kDa
Protein Sequence
Protein Sequence
>RC201210 protein sequence
Red=Cloning site Green=Tags(s)

MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSCIGKYLLLEPL
EGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSF
VRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLS
DKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPK
AKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_067675
RefSeq Size 4408
RefSeq ORF 1029
Synonyms C5FW; GS3955; TRB2
Locus ID 28951
UniProt ID Q92519
Cytogenetics 2p24.3
Summary This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Mar 2009
Protein Families Druggable Genome, Protein Kinase
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Other "TRIB2" proteins (3)
SKU Description Size Price
LC402872 Lyophilized TRIB2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402872 Transient overexpression lysate of tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP301210 Recombinant protein of human tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1, 20 µg 20 ug
$737.00

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