Human C9orf174 (CCDC180) activation kit by CRISPRa

SKU GA119271

CCDC180 CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 180

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CCDC180
• Locus ID: 100499483
• Components:

  GA119271G1, C9orf174 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA119271G2, C9orf174 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA119271G3, C9orf174 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_020893, NM_001348010
• UniProt ID: Q9P1Z9
• Synonyms: BDAG1; C9orf174; KIAA1529
• Summary: The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]