Human PP14397 (JMJD8) activation kit by CRISPRa

SKU GA117401

JMJD8 CRISPRa kit - CRISPR gene activation of human jumonji domain containing 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: JMJD8
• Locus ID: 339123
• Components:

  GA117401G1, PP14397 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117401G2, PP14397 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117401G3, PP14397 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001005920, NM_001323918, NM_001323919, NM_001323920, NM_001323922, NR_136650, NR_136651, NR_136652
• UniProt ID: Q96S16
• Synonyms: C16orf20; PP14397
• Summary: Functions as a positive regulator of TNF-induced NF-kappa-B signaling (PubMed:27671354). Regulates angiogenesis and cellular metabolism through interaction with PKM (PubMed:27199445).[UniProtKB/Swiss-Prot Function]