Human Repulsive Guidance Molecule B (RGMB) activation kit by CRISPRa

SKU GA117253

RGMB CRISPRa kit - CRISPR gene activation of human repulsive guidance molecule BMP co-receptor b

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RGMB
• Locus ID: 285704
• Components:

  GA117253G1, Repulsive Guidance Molecule B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117253G2, Repulsive Guidance Molecule B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117253G3, Repulsive Guidance Molecule B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001012761, NM_173670, NM_001366508, NM_001366509, NM_001366510, NM_001366511
• UniProt ID: Q6NW40
• Synonyms: DRAGON
• Summary: RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]