Human WDR51B (POC1B) activation kit by CRISPRa

SKU GA116969

POC1B CRISPRa kit - CRISPR gene activation of human POC1 centriolar protein B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: POC1B
• Locus ID: 282809
• Components:

  GA116969G1, WDR51B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116969G2, WDR51B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116969G3, WDR51B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001199777, NM_172240, NR_037659, NR_037660
• UniProt ID: Q8TC44
• Synonyms: CORD20; PIX1; TUWD12; WDR51B
• Summary: POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]