Human TAS2R48 (TAS2R19) activation kit by CRISPRa

SKU GA116924

TAS2R19 CRISPRa kit - CRISPR gene activation of human taste 2 receptor member 19

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TAS2R19
• Locus ID: 259294
• Components:

  GA116924G1, TAS2R48 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116924G2, TAS2R48 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116924G3, TAS2R48 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_176888
• UniProt ID: P59542
• Synonyms: MSTP058; T2R19; T2R23; T2R48; TAS2R23; TAS2R48
• Summary: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).[UniProtKB/Swiss-Prot Function]