Human FGD5 activation kit by CRISPRa

SKU GA115830

FGD5 CRISPRa kit - CRISPR gene activation of human FYVE, RhoGEF and PH domain containing 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FGD5
• Locus ID: 152273
• Components:

  GA115830G1, FGD5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115830G2, FGD5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115830G3, FGD5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001320276, NM_152536
• UniProt ID: Q6ZNL6
• Synonyms: ZFYVE23
• Summary: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.[UniProtKB/Swiss-Prot Function]