Human Desmoglein 4 (DSG4) activation kit by CRISPRa

SKU GA115608

DSG4 CRISPRa kit - CRISPR gene activation of human desmoglein 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DSG4
• Locus ID: 147409
• Components:

  GA115608G1, Desmoglein 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115608G2, Desmoglein 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115608G3, Desmoglein 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001134453, NM_177986
• UniProt ID: Q86SJ6
• Synonyms: CDGF13; CDHF13; HYPT6; LAH
• Summary: This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016]