Human Tau tubulin kinase 2 (TTBK2) activation kit by CRISPRa

SKU GA115542

TTBK2 CRISPRa kit - CRISPR gene activation of human tau tubulin kinase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TTBK2
• Locus ID: 146057
• Components:

  GA115542G1, Tau tubulin kinase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115542G2, Tau tubulin kinase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115542G3, Tau tubulin kinase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173500
• UniProt ID: Q6IQ55
• Synonyms: SCA11; TTBK
• Summary: This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. [provided by RefSeq, Aug 2009]