Human C20orf132 (MROH8) activation kit by CRISPRa

SKU GA115392

MROH8 CRISPRa kit - CRISPR gene activation of human maestro heat like repeat family member 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MROH8
• Locus ID: 140699
• Components:

  GA115392G1, C20orf132 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115392G2, C20orf132 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115392G3, C20orf132 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_152503, NM_213631, NM_213632
• UniProt ID: Q9H579
• Synonyms: C20orf131; C20orf132; dJ621N11.3; dJ621N11.4
• Summary: The protein encoded by this gene belongs to the maestro heat-like repeat family. The exact function of this gene is not known, however, in a genome-wide association study using hippocampal atrophy as a quantitative trait, this gene has been associated with Alzheimer's disease (PMID:19668339). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]