Human Myosin IIIB (MYO3B) activation kit by CRISPRa

SKU GA115370

MYO3B CRISPRa kit - CRISPR gene activation of human myosin IIIB

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MYO3B
• Locus ID: 140469
• Components:

  GA115370G1, Myosin IIIB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115370G2, Myosin IIIB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115370G3, Myosin IIIB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001083615, NM_001171642, NM_138995, NR_045682, NR_045683, NR_045684
• UniProt ID: Q8WXR4
• Synonyms: myosin IIIB
• Summary: This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]