Human PGRP1A (PGLYRP3) activation kit by CRISPRa

SKU GA114445

PGLYRP3 CRISPRa kit - CRISPR gene activation of human peptidoglycan recognition protein 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PGLYRP3
• Locus ID: 114771
• Components:

  GA114445G1, PGRP1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114445G2, PGRP1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114445G3, PGRP1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_052891
• UniProt ID: Q96LB9
• Synonyms: PGLYRPIalpha; PGRP-Ialpha; PGRPIA
• Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]