Human GGTLC1 activation kit by CRISPRa

SKU GA114178

GGTLC1 CRISPRa kit - CRISPR gene activation of human gamma-glutamyltransferase light chain 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GGTLC1
• Locus ID: 92086
• Components:

  GA114178G1, GGTLC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114178G2, GGTLC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114178G3, GGTLC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_080920, NM_178311, NM_178312
• UniProt ID: Q9BX51
• Synonyms: GGTLA3, GGTLA4, MGC50550, dJ831C21.1, dJ831C21.2
• Summary: This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]