Human GPR 174 (GPR174) activation kit by CRISPRa

SKU GA113621

GPR174 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 174

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GPR174
• Locus ID: 84636
• Components:

  GA113621G1, GPR 174 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113621G2, GPR 174 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113621G3, GPR 174 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_032553
• UniProt ID: Q9BXC1
• Synonyms: FKSG79; GPCR17; LYPSR3
• Summary: This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011]