Human Acetoacetyl CoA synthetase (AACS) activation kit by CRISPRa

SKU GA112268

AACS CRISPRa kit - CRISPR gene activation of human acetoacetyl-CoA synthetase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: AACS
• Locus ID: 65985
• Components:

  GA112268G1, Acetoacetyl CoA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112268G2, Acetoacetyl CoA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112268G3, Acetoacetyl CoA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001319839, NM_001319840, NM_023928
• UniProt ID: Q86V21
• Synonyms: ACSF1; SUR-5
• Summary: Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).[UniProtKB/Swiss-Prot Function]