Human ALS2CR1 (NIF3L1) activation kit by CRISPRa

SKU GA111858

NIF3L1 CRISPRa kit - CRISPR gene activation of human NGG1 interacting factor 3 like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NIF3L1
• Locus ID: 60491
• Components:

  GA111858G1, ALS2CR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111858G2, ALS2CR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111858G3, ALS2CR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001136039, NM_001142355, NM_001142356, NM_021824, NM_001369441, NM_001369442, NM_001369443, NM_001369444, NM_001369445
• UniProt ID: Q9GZT8
• Synonyms: ALS2CR1; CALS-7; MDS015
• Summary: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.[UniProtKB/Swiss-Prot Function]