Human SHROOM4 activation kit by CRISPRa

SKU GA111522

SHROOM4 CRISPRa kit - CRISPR gene activation of human shroom family member 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SHROOM4
• Locus ID: 57477
• Components:

  GA111522G1, SHROOM4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111522G2, SHROOM4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111522G3, SHROOM4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_020717, NR_027121
• UniProt ID: Q9ULL8
• Synonyms: SHAP
• Summary: This gene encodes a member of the APX/Shroom family, which contain an N-terminal PDZ domain and a C-terminal ASD2 motif. The encoded protein may play a role in cytoskeletal architecture. Mutations in this gene have been linked to the X-linked Stocco dos Santos syndrome characterized by cognitive disabilities. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2017]