Human Neurabin 1 (PPP1R9A) activation kit by CRISPRa

SKU GA110817

PPP1R9A CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 9A

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PPP1R9A
• Locus ID: 55607
• Components:

  GA110817G1, Neurabin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110817G2, Neurabin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110817G3, Neurabin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001166160, NM_001166161, NM_001166162, NM_001166163, NM_017650
• UniProt ID: Q9ULJ8
• Synonyms: Neurabin-I; NRB1; NRBI
• Summary: This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]