Human Phosphoserine Aminotransferase (PSAT1) activation kit by CRISPRa

SKU GA109349

PSAT1 CRISPRa kit - CRISPR gene activation of human phosphoserine aminotransferase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PSAT1
• Locus ID: 29968
• Components:

  GA109349G1, Phosphoserine Aminotransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109349G2, Phosphoserine Aminotransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109349G3, Phosphoserine Aminotransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021154, NM_058179
• UniProt ID: Q9Y617
• Synonyms: EPIP; NLS2; PSA; PSAT; PSATD
• Summary: This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8. [provided by RefSeq, Jul 2013]