Human Nucleostemin (GNL3) activation kit by CRISPRa

SKU GA108861

GNL3 CRISPRa kit - CRISPR gene activation of human G protein nucleolar 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNL3
• Locus ID: 26354
• Components:

  GA108861G1, Nucleostemin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108861G2, Nucleostemin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108861G3, Nucleostemin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_014366, NM_206825, NM_206826
• UniProt ID: Q9BVP2
• Synonyms: C77032; E2IG3; NNP47; NS
• Summary: The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]