Human GBGT1 activation kit by CRISPRa

SKU GA108854

GBGT1 CRISPRa kit - CRISPR gene activation of human globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GBGT1
• Locus ID: 26301
• Components:

  GA108854G1, GBGT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108854G2, GBGT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108854G3, GBGT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001282629, NM_001282632, NM_001288572, NM_001288573, NM_021996
• UniProt ID: Q8N5D6
• Synonyms: A3GALNT; FS; UNQ2513
• Summary: This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]