Human Kallikrein 13 (KLK13) activation kit by CRISPRa

SKU GA108741

KLK13 CRISPRa kit - CRISPR gene activation of human kallikrein related peptidase 13

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: KLK13
• Locus ID: 26085
• Components:

  GA108741G1, Kallikrein 13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108741G2, Kallikrein 13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108741G3, Kallikrein 13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015596, NM_001348177, NM_001348178, NR_145463, NR_145464, NR_145465, NR_145466, NR_145467
• UniProt ID: Q9UKR3
• Synonyms: KLK-L4; KLKL4
• Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. [provided by RefSeq, Jan 2017]