Human WDR51A (POC1A) activation kit by CRISPRa

SKU GA108606

POC1A CRISPRa kit - CRISPR gene activation of human POC1 centriolar protein A

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: POC1A
• Locus ID: 25886
• Components:

  GA108606G1, WDR51A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108606G2, WDR51A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108606G3, WDR51A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001161580, NM_001161581, NM_015426
• UniProt ID: Q8NBT0
• Synonyms: PIX2; SOFT; WDR51A
• Summary: POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012]