Human Encephalopsin (OPN3) activation kit by CRISPRa

SKU GA108424

OPN3 CRISPRa kit - CRISPR gene activation of human opsin 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: OPN3
• Locus ID: 23596
• Components:

  GA108424G1, Encephalopsin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108424G2, Encephalopsin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108424G3, Encephalopsin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001030011, NM_001030012, NM_014322
• UniProt ID: Q9H1Y3
• Synonyms: ECPN; encephalopsin; opsin 3; opsin 3 (encephalopsin, panopsin); OTTHUMP00000037645
• Summary: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]