Human ZDHHC17 activation kit by CRISPRa

SKU GA108272

ZDHHC17 CRISPRa kit - CRISPR gene activation of human zinc finger DHHC-type containing 17

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ZDHHC17
• Locus ID: 23390
• Components:

  GA108272G1, ZDHHC17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108272G2, ZDHHC17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108272G3, ZDHHC17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015336, NM_001359626
• UniProt ID: Q8IUH5
• Synonyms: HIP3; HIP14; HSPC294; HYPH
• Summary: Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HTT (PubMed:15603740, PubMed:15489887, PubMed:19139280, PubMed:28757145). May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane (PubMed:12393793). May play a role in Mg(2+) transport (PubMed:18794299).[UniProtKB/Swiss-Prot Function]