Human Frizzled 10 (FZD10) activation kit by CRISPRa

SKU GA107721

FZD10 CRISPRa kit - CRISPR gene activation of human frizzled class receptor 10

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FZD10
• Locus ID: 11211
• Components:

  GA107721G1, Frizzled 10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107721G2, Frizzled 10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107721G3, Frizzled 10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_007197
• UniProt ID: Q9ULW2
• Synonyms: CD350; FZ-10; Fz10; FzE7; hFz10
• Summary: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]