Human WDHD1 activation kit by CRISPRa

SKU GA107691

WDHD1 CRISPRa kit - CRISPR gene activation of human WD repeat and HMG-box DNA binding protein 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: WDHD1
• Locus ID: 11169
• Components:

  GA107691G1, WDHD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107691G2, WDHD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107691G3, WDHD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001008396, NM_007086
• UniProt ID: O75717
• Synonyms: AND-1; AND1; CHTF4; CTF4
• Summary: The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]