Human katanin p80 (KATNB1) activation kit by CRISPRa

SKU GA107020

KATNB1 CRISPRa kit - CRISPR gene activation of human katanin regulatory subunit B1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: KATNB1
• Locus ID: 10300
• Components:

  GA107020G1, katanin p80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107020G2, katanin p80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107020G3, katanin p80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005886
• UniProt ID: Q9BVA0
• Synonyms: KAT; LIS6
• Summary: Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008]