Human KIAA0528 (C2CD5) activation kit by CRISPRa

SKU GA106639

C2CD5 CRISPRa kit - CRISPR gene activation of human C2 calcium dependent domain containing 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: C2CD5
• Locus ID: 9847
• Components:

  GA106639G1, KIAA0528 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106639G2, KIAA0528 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106639G3, KIAA0528 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001286173, NM_001286174, NM_001286175, NM_001286176, NM_001286177, NM_014802
• UniProt ID: Q86YS7
• Synonyms: CDP138; KIAA0528
• Summary: Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.[UniProtKB/Swiss-Prot Function]