Human CART (CARTPT) activation kit by CRISPRa

SKU GA106432

CARTPT CRISPRa kit - CRISPR gene activation of human CART prepropeptide

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CARTPT
• Locus ID: 9607
• Components:

  GA106432G1, CART gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106432G2, CART gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106432G3, CART gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004291
• UniProt ID: Q16568
• Synonyms: CART
• Summary: This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016]