Human Surb7 (MED21) activation kit by CRISPRa

SKU GA106282

MED21 CRISPRa kit - CRISPR gene activation of human mediator complex subunit 21

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MED21
• Locus ID: 9412
• Components:

  GA106282G1, Surb7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106282G2, Surb7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106282G3, Surb7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001271811, NM_004264, NR_073463, NR_073464
• UniProt ID: Q13503
• Synonyms: hSrb7; SRB7; SURB7
• Summary: This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]