Human Transglutaminase 5 (TGM5) activation kit by CRISPRa

SKU GA106222

TGM5 CRISPRa kit - CRISPR gene activation of human transglutaminase 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TGM5
• Locus ID: 9333
• Components:

  GA106222G1, Transglutaminase 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106222G2, Transglutaminase 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106222G3, Transglutaminase 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004245, NM_201631
• UniProt ID: O43548
• Synonyms: PSS2; TGASE5; TGASEX; TGM6; TGMX; TGX
• Summary: This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009]