Human Mupp1 (MPDZ) activation kit by CRISPRa

SKU GA105828

MPDZ CRISPRa kit - CRISPR gene activation of human multiple PDZ domain crumbs cell polarity complex component

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MPDZ
• Locus ID: 8777
• Components:

  GA105828G1, Mupp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105828G2, Mupp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105828G3, Mupp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001261406, NM_001261407, NM_001330637, NM_003829
• UniProt ID: O75970
• Synonyms: HYC2; MUPP1
• Summary: The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]