Human PIP5K1 beta (PIP5K1B) activation kit by CRISPRa

SKU GA105545

PIP5K1B CRISPRa kit - CRISPR gene activation of human phosphatidylinositol-4-phosphate 5-kinase type 1 beta

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PIP5K1B
• Locus ID: 8395
• Components:

  GA105545G1, PIP5K1 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105545G2, PIP5K1 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105545G3, PIP5K1 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001031687, NM_001278253, NM_003558
• UniProt ID: O14986
• Synonyms: MSS4; MSS4, STM7; OTTHUMP00000021423; phosphatidylinositol-4-phosphate 5-kinase, type I, beta; STM7
• Summary: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity).[UniProtKB/Swiss-Prot Function]