Human TRH Receptor (TRHR) activation kit by CRISPRa

SKU GA104973

TRHR CRISPRa kit - CRISPR gene activation of human thyrotropin releasing hormone receptor

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TRHR
• Locus ID: 7201
• Components:

  GA104973G1, TRH Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104973G2, TRH Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104973G3, TRH Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003301
• UniProt ID: P34981
• Synonyms: TRH-R
• Summary: This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]