Human Triosephosphate isomerase (TPI1) activation kit by CRISPRa

SKU GA104951

TPI1 CRISPRa kit - CRISPR gene activation of human triosephosphate isomerase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TPI1
• Locus ID: 7167
• Components:

  GA104951G1, Triosephosphate isomerase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104951G2, Triosephosphate isomerase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104951G3, Triosephosphate isomerase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000365, NM_001159287, NM_001258026, NR_027483
• UniProt ID: P60174
• Synonyms: HEL-S-49; TIM; TPI; TPID
• Summary: This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]