Human COUP TF1 (NR2F1) activation kit by CRISPRa

SKU GA104834

NR2F1 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 2 group F member 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NR2F1
• Locus ID: 7025
• Components:

  GA104834G1, COUP TF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104834G2, COUP TF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104834G3, COUP TF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005654
• UniProt ID: P10589
• Synonyms: BBOAS; BBSOAS; COUP-TFI; EAR-3; EAR3; ERBAL3; NR2F2; SVP44; TCFCOUP1; TFCOUP1
• Summary: The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014]