Human PKI alpha (PKIA) activation kit by CRISPRa

SKU GA103761

PKIA CRISPRa kit - CRISPR gene activation of human cAMP-dependent protein kinase inhibitor alpha

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PKIA
• Locus ID: 5569
• Components:

  GA103761G1, PKI alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103761G2, PKI alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103761G3, PKI alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006823, NM_181839
• UniProt ID: P61925
• Synonyms: PRKACN1
• Summary: The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]