Human Plexin B1 (PLXNB1) activation kit by CRISPRa

SKU
GA103621
PLXNB1 CRISPRa kit - CRISPR gene activation of human plexin B1
$1,657.00
2 Weeks*
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PLXNB1
Locus ID 5364
Components

GA103621G1, Plexin B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103621G2, Plexin B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103621G3, Plexin B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001130082, NM_002673
UniProt ID O43157
Synonyms PLEXIN-B1; PLXN5; SEP
Summary Receptor for SEMA4D (PubMed:19843518, PubMed:20877282, PubMed:21912513). Plays a role in GABAergic synapse development (By similarity). Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12196628, PubMed:15210733). Plays a role in axon guidance, invasive growth and cell migration (PubMed:12198496).[UniProtKB/Swiss-Prot Function]
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SKU Description Size Price
KN424819 PLXNB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.