Human Homeobox protein SIX6 (SIX6) activation kit by CRISPRa

SKU GA103326

SIX6 CRISPRa kit - CRISPR gene activation of human SIX homeobox 6

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SIX6
• Locus ID: 4990
• Components:

  GA103326G1, Homeobox protein SIX6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103326G2, Homeobox protein SIX6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103326G3, Homeobox protein SIX6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_007374
• UniProt ID: O95475
• Synonyms: MCOPCT2; ODRMD; OPTX2; Six9
• Summary: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2). [provided by RefSeq, Jul 2008]