Human NK TR protein (NKTR) activation kit by CRISPRa

SKU GA103215

NKTR CRISPRa kit - CRISPR gene activation of human natural killer cell triggering receptor

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NKTR
• Locus ID: 4820
• Components:

  GA103215G1, NK TR protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103215G2, NK TR protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103215G3, NK TR protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001012651, NM_005385, NM_001349124, NM_001349125, NM_001349126
• UniProt ID: P30414
• Synonyms: DKFZp686F1754; DKFZp686G0426; DKFZp686J06106; DKFZp686N24126; MGC90527; p104
• Summary: This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008]