Human ASD3 (MYH6) activation kit by CRISPRa

SKU GA103066

MYH6 CRISPRa kit - CRISPR gene activation of human myosin heavy chain 6

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MYH6
• Locus ID: 4624
• Components:

  GA103066G1, ASD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103066G2, ASD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103066G3, ASD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002471
• UniProt ID: P13533
• Synonyms: alpha-MHC; ASD3; CMD1EE; CMH14; MYHC; MYHCA; SSS3
• Summary: Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Feb 2017]