Human myosin heavy chain 3 (MYH3) activation kit by CRISPRa

SKU GA103064

MYH3 CRISPRa kit - CRISPR gene activation of human myosin heavy chain 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MYH3
• Locus ID: 4621
• Components:

  GA103064G1, myosin heavy chain 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103064G2, myosin heavy chain 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103064G3, myosin heavy chain 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002470
• UniProt ID: P11055
• Synonyms: DA2A; DA2B; DA8; HEMHC; MYHC-EMB; MYHSE1; SMHCE
• Summary: Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008]