Human Methionyl tRNA synthetase (MARS) activation kit by CRISPRa

SKU GA102819

MARS CRISPRa kit - CRISPR gene activation of human methionyl-tRNA synthetase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MARS1
• Locus ID: 4141
• Components:

  GA102819G1, Methionyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102819G2, Methionyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102819G3, Methionyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004990
• UniProt ID: P56192
• Synonyms: CMT2U; ILFS2; ILLD; METRS; MRS; MTRNS; SPG70
• Summary: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011]