Human Cytokeratin 17 (KRT17) activation kit by CRISPRa

SKU GA102626

KRT17 CRISPRa kit - CRISPR gene activation of human keratin 17

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: KRT17
• Locus ID: 3872
• Components:

  GA102626G1, Cytokeratin 17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102626G2, Cytokeratin 17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102626G3, Cytokeratin 17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000422
• UniProt ID: Q04695
• Synonyms: 39.1; CK-17; K17; PC; PC2; PCHC1
• Summary: This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]