Human Homeo box C10 (HOXC10) activation kit by CRISPRa

SKU GA102209

HOXC10 CRISPRa kit - CRISPR gene activation of human homeobox C10

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: HOXC10
• Locus ID: 3226
• Components:

  GA102209G1, Homeo box C10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102209G2, Homeo box C10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102209G3, Homeo box C10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_017409
• UniProt ID: Q9NYD6
• Synonyms: HOX3I
• Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation. [provided by RefSeq, Jul 2008]