Human Glutathione S Transferase theta 2 (GSTT2) activation kit by CRISPRa

SKU GA101999

GSTT2 CRISPRa kit - CRISPR gene activation of human glutathione S-transferase theta 2 (gene/pseudogene)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GSTT2
• Locus ID: 2953
• Components:

  GA101999G1, Glutathione S Transferase theta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101999G2, Glutathione S Transferase theta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101999G3, Glutathione S Transferase theta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000854, NM_001302670, NR_126442, NR_126445, NR_126446
• UniProt ID: P0CG29
• Synonyms: GSTT2B
• Summary: The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015]